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New compound more effective in treating heart rhythm disorder

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작성자 dermamall 작성일18-12-12 14:14 조회606회 댓글0건



New compound more effective in treating heart rhythm disorder

 Man-tik Choy December 11, 2018

A recent pre-clinical study showed that a new aminoindole derivative, SS-68, could effectively treat heart rhythm disorders by bringing the electrical activity of the heart back to normal. Heart rhythm disorder, as known as cardiac arrhythmia, is a disorder that affects the normal heart rate. A normal resting heart rate for an adult ranges from60 to 100 beats per minute. With a heart rhythm disorder, the heart tends to beat too slow, too fast, or irregularly. It is caused when the electrical signal paths within the heart are interrupted or disturbed.


Heart rhythm disorder may not cause any signs or symptoms, while some people may experience an irregular heartbeat, shortness of breath, chest pain, dizziness, and paleness. This heart disease increases the risk of stroke and heart attack, and largely affecting the quality of one’s life. Many drugs are available in treating and managing arrhythmias, by controlling the heart rate and rhythm or helping to prevent blood clots. However, existing antifibrillatory drugs have a narrow window between their effective doses and those at which they produce adverse toxic effects.


In brain injury-induced heart rhythm disorders, the researchers further observed that the compound can reduce spike waves, sharp waves, spike and wave activities. The compound also has a profound effect in treating clogged blood vessels by increasing the coronary blood flow. SS-68 compound is a promising pharmacological agent in treating heart rhythm disorder. Further thorough research on the associated side effects and adverse events is still needed before we can conclude that this new compound is safe and effective.


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